秋山 久尚の業績　神経難病の研究・治療に実績多数。充実した研修医育成システム　聖マリアンナ医科大学脳神経内科学

●Ishikawa H, Kezuka T, Shikishima K, Yamagami A, Hiraoka M, Chuman H, Nakamura M, Hoshi K, Goseki T, Mashimo K, Mimura O, Yoshitomi T, Tanaka K; Working Group on Diagnostic Criteria for Refractory Optic Neuritis Based on Neuroimmunological Perspective.
Epidemiologic and Clinical Characteristics of Optic Neuritis in Japan.
Ophthalmology. 2019 Oct;126(10):1385-1398.

 

●Nukui S, Akiyama H, Soga K, Takao N, Tsuchihashi Y, Iijima N, Hasegawa Y.
Risk of Hyperglycemia and Hypoglycemia in Patients with Acute Ischemic Stroke Based on Continuous Glucose Monitoring.
Journal of Stroke and Cerebrovascular Diseases 2019 in press

 

●Akiyama H, Hasegawa Y.
Effectiveness of the traditional Japanese Kampo medicine Yokukansan for chronic migraine.
Medicine(Baltimore) 2019 Sep;98（39）：e17380

 

●Hoshino M, Akiyama H, Kashima S, Soga K, Shimizu T, Hasegawa Y.
Acute onset bilateral hearing loss in dorsomedial pontine hemorrhage: A Case report.
Medicine (Baltimore). 2019 Aug;98(34):e16902

 

●Hara D, Nukui S, Shimizu T, Akiyama H, Hasegawa Y.
Reversible Cerebral Vasoconstriction Syndrome after Administering Etanercept during Puerperium.
J Stroke Cerebrovasc Dis. 2019 Apr;28(4):e10-e11

 

●Akiyama H, Sasaki R, Hasegawa Y.
Efficacy of perampanel for anti-N-methyl-D-aspartate receptor encephalitis: A case report.
Medicine(Baltimore)2019 Jan;98(2):e14033

 

●Kashima S, Shimizu T, Akiyama H, Hasegawa Y.
Magnetic Resonance Imaging White Matter Hyperintensity as a Predictor of Stroke Recurrence in Patients with Embolic Stroke of Undetermined Source.
J Stroke Cerebrovasc Dis. 2018 　27（12）：3613-3620

 

●Akamatsu M, Maki F, Akiyama H, Hara D, Hoshino M, Hasegawa Y.
Rheumatoid meningitis presenting with a stroke-like attack treated with recombinant tissue plasminogen activator: a case presentation.
BMC Neurol. 2018 Sep 6;18(1):139. doi: 10.1186/s12883-018-1143-z.

 

●Hagiwara Y, Sasaki R, Shimizu T, Soga K, Hatada C, Miyauchi M,
Okamura T, Sakurai M, Akiyama H, Hasegawa Y.
The utility of superb microvascular imaging for the detection of deep vein thrombosis.
J Med Ultrason (2001). 2018 Oct;45(4):665-669. doi: 10.1007/s10396-018-0883-0. Epub 2018 May 17.

 

●Akiyama H, Hasegawa Y.
Awareness of atrial fibrillation in Japan: A large-scale, nationwide Internet survey of 50 000 Japanese adults. Geriatr Gerontol Int. 2018 Jul;18(7):1100-1107. doi: 10.1111/ggi.13318. Epub 2018 Mar 30.

 

●Akiyama H, Hasegawa Y.
A trial case of medical treatment for primary headache using telemedicine.Medicine(Baltimore). 2018 Jan;97(9)e9891

 

●Hara D, Akiyama H, Nukui S, Shimizu T, Hoshikawa M, Hasegawa Y.
Utility of osteosclerotic lesion biopsy in diagnosis of POEMS syndrome: A case report.
Medicine (Baltimore). 2017 Oct;96(41):e8188. doi: 10.1097/MD.0000000000008188.PMID:29019884

 

●Akiyama H, Nukui S, Akamatu M, Hasegawa Y, Nishikido O, Inoue S. Effectiveness of spinal cord stimulation for painful camptocormia with Pisa syndrome in Parkinson's disease: a case report.
BMC Neurol. 2017 Aug 3;17(1):148. doi: 10.1186/s12883-017-0926-y.

 

●Isahaya K, Kawakami T, Shiraishi M, Akiyama H, Hasegawa Y.
Nerve conduction study of lower extremities in cutaneous arteritis patients with neurological manifestations.
J Dermatol. 2017 Jun 30. doi: 10.1111/1346-8138.13946.

 

●Isahaya K, Shinohara K, Akamatu M, Shimizu T, Sakurai K, Shiraishi M, Akiyama H, Hasegawa Y.
Reversible Cerebral Vasoconstriction Syndrome Presenting with Transient Global Amnesia.
Intern Med. 2017;56(12):1569-1573. doi: 10.2169/internalmedicine.56.7460. Epub 2017 Jun 15.

 

●Akiyama H, Nukui S, Araga T, Hoshino M, Tanaka K, Kashima S, Sasaki R, Uchino K, Hasegawa Y.
Utility of Duranta, a wireless patch-type electrocardiographic monitoring system developed in Japan, in detecting covert atrial fibrillation in patients with cryptogenic stroke: A case report.
Medicine (Baltimore). 2017 Feb;96(6):e5995. doi: 10.1097/MD.0000000000005995.

 

●Kenji Isahaya, Kensuke Shinohara, Masashi Akamatu, Takahiro Shimizu, Kenzo Sakurai, Makoto Shiraishi, Akiyama H and Yasuhiro Hasegawa.
Reversible cerebral vasoconstriction syndrome presenting with transient global amnesia.
Intern Med 56: 1569-1573, 2017.

 

●Tsuruoka A, Shiraishi M, Tanaka K, Akamatsu M, Shinohara K, Akiyama H, Hasegawa Y.

A case of familial prion disease diagnosed as Alzheimer’s disease for 5 years.

J. St. Marianna Univ. 2016;7:125-9.

 

●Akiyama H, Suzuki Y, Hara D, Shinohara K, Ogura H, Akamatsu M, Hasegawa Y.

Improvement of macular edema without discontinuation of fingolimod in a patient with multiple sclerosis: A case report.

Medicine (Baltimore). 2016 Jul;95(29):e4180. doi: 10.1097/MD.0000000000004180.

 

●Akiyama H, Hoshino M, Shimizu T, Hasegawa Y.

Resolution of Internal Carotid Arterial Thrombus by the Thrombolytic Action of Dabigatran: A first case report.

Medicine (Baltimore). 2016 Apr;95(14):e3215. doi: 10.1097/MD.0000000000003215.

 

●Hosomi N, Nagai Y, Kohriyama T, Ohtsuki T, Aoki S, Nezu T, Maruyama H, Sunami N, Yokota C, Kitagawa K, Terayama Y, Takagi M, Ibayashi S, Nakamura M, Origasa H, Fukushima M, Mori E, Minematsu K, Uchiyama S, Shinohara Y, Yamaguchi T, Matsumoto M; J-STARS Collaborators.

The Japan Statin Treatment Against Recurrent Stroke (J-STARS): A Multicenter, Randomized, Open-label, Parallel-group Study.

EBioMedicine. 2015 Aug 6;2(9):1071-8. doi: 10.1016/j.ebiom.2015.08.006.

 

●Akiyama H, Uchino K, Hasegawa Y.

Characteristics of Symptomatic Intracranial Hemorrhage in Patients Receiving Non-Vitamin K Antagonist Oral Anticoagulant Therapy.

PLoS One. 2015 Jul 14;10(7):e0132900. doi: 10.1371/journal.pone.0132900.

 

●Akiyama H, Haga Y, Sasaki N, Yanagisawa T, Hasegawa Y.

A case of rhabdomyolysis in which levetiracetam was suspected as the cause.

Epilepsy Behav Case Rep. 2014 Sep 16;2:152-5. doi: 10.1016/j.ebcr.2014.08.001.

 

●Tsuchiya A, Akiyama H, Hasegawa Y.

Spinal sarcoidosis presenting with epiconus syndrome.

Intern Med. 2014;53(21):2529-32.

 

●Hagiwara Y, Imai T, Yamada K, Sakurai K, Atsumi C, Tsuruoka A, Mizukami H, Sasaki N, Akiyama H, Hasegawa Y.

Impact of life and family background on delayed presentation to hospital in acute stroke.

J Stroke Cerebrovasc Dis. 2014 Apr;23(4):625-9. doi: 10.1016/j.jstrokecerebrovasdis.2013.05.034.

 

●Akiyama H, Hasegawa Y.

Corporate understanding of the significance of headache: A survey of managers of Japanese pharmaceutical and health-related companies. International Journal of Pain. 2013;4(1): 8-14.

 

●Akiyama H, Hasegawa Y.

Knowledge of transient ischemic attack among the Japanese.

J Stroke Cerebrovasc Dis. 2013 May;22(4):457-64. doi: 10.1016/j.jstrokecerebrovasdis.2013.03.017.

 

●Akiyama H, Hasegawa Y.

Stroke knowledge: a nationwide, internet-based survey of 11,121 inhabitants in Japan.

Intern Med. 2013;52(5):529-37.

 

●Akiyama H, Hasegawa Y.

Migraine treated using a prophylactic combination of candesartan and hydrochlorothiazide (ECARD Combination Tablets LD).

Pain Pract. 2013 Sep;13(7):566-71. doi: 10.1111/papr.12005.

 

●Harada Y, Akiyama H, Yoshimoto T, Urao Y, Ryuzaki M, Handa M.

Thyroid storm with multiple organ failure, disseminated intravascular coagulation, and stroke with a normal serum FT3 level.

Intern Med. 2012;51(17):2379-83.

 

●Akiyama H.

Inconsistent detection of subhyaloid hemorrhage in the globe using computed tomography.

Emerg Radiol. 2012 Jun;19(3):269-72. doi: 10.1007/s10140-012-1021-8.

 

●Shinohara Y, Katayama Y, Uchiyama S, Yamaguchi T, Handa S, Matsuoka K, Ohashi Y, Tanahashi N, Yamamoto H, Genka C, Kitagawa Y, Kusuoka H, Nishimaru K, Tsushima M, Koretsune Y, Sawada T, Hamada C; CSPS 2 group.

Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial.

Lancet Neurol. 2010 Oct;9(10):959-68. doi: 10.1016/S1474-4422(10)70198-8.

 

●Uchiyama S, Shibata Y, Hirabayashi T, Mihara B, Hamashige N, Kitagawa K, Goto S, Origasa H, Shimada K, Kobayashi H, Isozaki M, Ikeda Y; J-TRACE Investigators.

Risk factor profiles of stroke, myocardial infarction, and atrial fibrillation: a Japanese Multicenter Cooperative Registry.

J Stroke Cerebrovasc Dis. 2010 May;19(3):190-7. doi: 10.1016/j.jstrokecerebrovasdis.2009.04.004.

 

●Inoue H, Nozawa T, Hirai T, Goto S, Origasa H, Shimada K, Uchiyama S, Hirabayashi T, Koretsune Y, Ono S, Hasegawa T, Sasagawa Y, Kaneko Y, Ikeda Y; J-TRACE Investigators.

Sex-related differences in the risk factor profile and medications of patients with atrial fibrillation recruited in J-TRACE.

Circ J. 2010 Apr;74(4):650-4.

 

●Origasa H, Goto S, Uchiyama S, Shimada K, Ikeda Y; J-TRACE Investigators.

The Japan Thrombosis Registry for Atrial Fibrillation, Coronary or Cerebrovascular Events (J-TRACE): a nation-wide, prospective large cohort study; the study design.

Circ J. 2008 Jun;72(6):991-7.

 

●Meyer JS, Rauch GM, Mortel KF, Rauch RA, Haque A, Akiyama H, Konno S, Terayama Y.

Risk factors for vascular dementia．

J Stroke Cerebrovasc Dis. 2000;9(2):37-8.

 

●Meyer JS, Rauch GM, Crawford K, Rauch RA, Konno S, Akiyama H, Terayama Y, Haque A.

Risk factors accelerating cerebral degenerative changes, cognitive decline and dementia．

Int J Geriatr Psychiatry. 1999 Dec;14(12):1050-61.

 

●Meyer JS, Terayama Y, Konno S, Margishvili GM, Akiyama H, Rauch RA, Mortel KF, Wills PM.

Age-related cerebrovascular disease alters the symptomatic course of migraine.

Cephalalgia. 1998 May;18(4):202-8.

 

●Meyer JS, Terayama Y, Konno S, Akiyama H, Margishvili GM, Mortel KF.

Risk factors for cerebral degenerative changes and dementia.

Eur Neurol. 1998;39(suppl 1):7-16.

 

●Akiyama H, Meyer JS, Mortel KF, Terayama Y, Thornby JI, Konno S.

Normal human aging: Factors contributing to cerebral atrophy.

J Neurol Sci. 1997 Nov 6;152(1):39-49．

 

●Meyer JS, Akiyama H, Mortel KF, Konno S, Margishvili GM.

Human aging: risk factors for cerebral atrophy.

Ann N Y Acad Sci. 1997 Sep 26;826:483-9.

 

●Meyer JS, Shirai T, Mortel KF, Muramatsu K, Akiyama H.

Testing Xe/CT CBF cerebrovascular reserve for identifying migraine and differentiating Alzheimer’s from vascular dementia.

Acta Neurol Scand. 1996;166:148-9.

 

●Shirai T, Meyer JS, Akiyama H, Mortel KF, Wills PM.

Acetazolamide testing of cerebral vasodilator capacity provokes “vascular” but not tension headaches.

Headache. 1996 Nov-Dec;36(10):589-94.

 

●Meyer JS, Shirai T, Akiyama H.

Neuroimaging for differentiating vascular from Alzheimer’s dementias.

Cerebrovasc Brain Metab Rev. 1996 Spring;8(1):1-10.

 

●Masuda T, Akiyama H, Kurosawa T, Ohwada T.

Long-term follow-up of coronary artery dissection due to blunt chest trauma with spontaneous healing in a young woman.

Intensive Care Med. 1996;22:450-2.

 

●Akiyama H, Misu Y, Yoshida T, Tanaka T, Endo M, Soma K.

CT of Subarachnoid Hemorrhage with Subhyaloid Hemorrhage.

J Comput Assist Tomogr. 1995 Mar-Apr;19(2):327-9.

 

和文業績

●星野 俊, 鈴木 祐, 秋山久尚,　山田浩史,　島 さゆり,　武藤多津郎,　長谷川泰弘.
抗Galactocerebroside抗体陽性の中枢末梢連合脱髄症にステロイドパルス療法が奏功した1例.
臨床神経学. 2017; 57(12):747-752. doi: 10.5692/clinicalneurol.cn-000977

●秋山久尚, 貫井咲希, 荒賀祟, 星野俊, 田中啓太, 鹿島悟, 佐々木梨衣, 内野賢治, 長谷川泰弘 .

潜因性脳梗塞患者の塞栓源検索における前胸部貼付型テレメトリー式心電送信機duranta®の有用性.

日本遠隔医療学会雑誌. 2016；12(2):138-141

 

●土屋敦史, 富永泰弘, 鈴木孝昭, 芳賀吉輝, 大島　淳, 秋山久尚, 長谷川泰弘 .

頸椎前方固定プレート除去術が契機となって発症した内頸動脈解離の一例.

脳卒中. 2016；38(3):172

 

●秋山久尚. 

SAMURAI-ICH(Stroke Acute Management with Urgent Risk-factor Assessment and Improvement-Intracerebral Hemorrhage)研究サブ解析　―抗血栓薬服用と血腫増大―.

脳循環代謝. 2016；27(2):287-291

 

●伊佐早健司, 櫻井謙三, 加藤貴之, 今井健, 徳山承明, 吉江智秀, 清水眞, 内野賢治, 赤松真志, 秋山久尚, 長谷川泰弘. 

Telestroke Network 導入の潜在需要と導入の課題－静岡県におけるアンケート調査から

脳卒中. 2015；37(2):83-88

 

●土屋敦史, 鈴木孝昭, 渡邉裕文, 大島 淳, 秋山久尚, 長谷川泰弘.

単純CTにおいて静脈洞内の異なる吸収域が混在する所見が脳静脈洞血栓症を疑わせた1例.

脳卒中. 2015；37(1):17-20

 

●秋山久尚.

抗血栓薬服用と血腫の増大－SAMURAI-ICH研究サブ解析－.

神経内科. 2014；81(5):557-563

 

●白石 眞,秋山久尚.

神経内科医から見た神経眼科 ～パーキンソン病における視覚機能不全～.

神経眼科. 2014；31(3):344-349　

 

●秋山久尚. 　

神経眼科入門シリーズ 神経内科医から見た神経眼科 ～神経眼科医が知っておきたい多発性硬化症の最新知見～.

神経眼科. 2014；31(2):222-232

 

●秋山久尚, 白石　眞, 長谷川泰弘.

多発性硬化症に対するフィンゴリモド導入例における有効性と安全性の短期的評価.

神経眼科. 2014；31(2):205-213

 

●眞木二葉, 秋山久尚, 長谷川泰弘.

ベーチェット病に合併した肥厚性硬膜炎による頭痛の1症例.

日本頭痛学会誌. 2013；39(3):329-332

 

●柳澤俊之, 秋山久尚, 長谷川泰弘.

急性弛緩性麻痺を呈する患者における血清抗GD1a抗体陽性の臨床的意義.

聖マリアンナ医科大学雑誌. 2013；40(4):243-249

 

●伊佐早健司, 秋山久尚, 柳澤俊之, 堀内正浩, 長谷川泰弘.

甲状腺眼症に重症筋無力症、抗GAD抗体陽性を合併した自己免疫性内分泌腺症候群（APS)Ⅲ型の一例.

神経眼科. 2012；29(3):316-322

 

●秋山久尚.

基礎疾患をもたない高齢者に発症したリステリア(Listeria monocytogenes)髄膜炎の1例.

日本臨床救急医学会雑誌.2011； 14(6):656-661

 

●秋山久尚, 長谷川泰弘.

Over The Counter Drug(OTC医薬品)であるロート鼻炎ソフトカプセル　ユアⓇNの服用を契機に発症した横紋筋融解症の1症例.

日本臨床救急医学会雑誌. 2010；13(5):650-655